The Src tyrosine kinase pathway regulates thecal CYP17 expression and androstenedione secretion
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چکیده
منابع مشابه
Inhibition of thecal androstenedione
Implants ofprogesterone on the day ofdioestrus II in the hamster induced on the following day an increase in circulating levels of progesterone (6\m=.\0\m=+-\0\m=.\7ng/ml, N = 8; sesame oil controls, <0.5 ng/ml, N = 6) and a decline in serum levels of LH (5\m=.\3\m=+-\0\m=.\4ng/ml; controls 12 \m=+-\2 ng/ml) and oestradiol (10 \m=+-\2 pg/ml ; controls 69 \m=+-\5 pg/ml). The production of andros...
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Src and Src-family protein kinases are proto-oncogenes that play key roles in cell morphology, motility, proliferation, and survival. v-Src (a viral protein) is encoded by the chicken oncogene of Rous sarcoma virus, and Src (the cellular homologue) is encoded by a physiological gene, the first of the proto-oncogenes. From the N- to C-terminus, Src contains an N-terminal 14-carbon myristoyl grou...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biochemistry
سال: 2008
ISSN: 0300-8177,1573-4919
DOI: 10.1007/s11010-008-9871-9